What’s Wrong with How Autoimmune Disease is
Treated?
As I write this we are just
concluding the week-long Gluten eSummit, a first of its kind free event that
involves researchers from all over the world, all experts in the field of
gluten. The Summit’s creator and host is a dear friend, Dr Tom O’Bryan. If you’ve
ever attended one of my Gluten Sensitivity & Celiac Forums, or watched a
DVD from one, you’ve had the pleasure of watching Dr O’Bryan lecture.
In this post I wanted to share with
you my ‘take’ on one of the interviews at the Summit because it addresses a set
of diseases that I feel very, very strongly about – Autoimmune Diseases. I blog
about autoimmune often and have several YouTube videos on the topic as well.
Yet, we need to continue to discuss this condition that manifests itself in
over 100 different diseases, including celiac disease, because it is on the
rise. Currently, after heart disease and cancer, autoimmune diseases are the third leading
cause of death in this country.
Autoimmune incidence is not only
increasing rapidly, but the rationale and protocols utilized in our medical
community really miss the mark in my opinion – and my opinion, I am happy to
share, is echoed not only by Dr O’Bryan, but his guest Dr Aristo Vodjani, a
world renown immunologist. Obviously if anyone should understand the inner
workings of the immune system and why it would attack the human body (the
definition of autoimmune disease), it would be Dr Vodjani.
If You Want the Right Answer,
You Have to Ask the Right Question
It’s important to understand that
there are several aspects to the immune system. Dr O’Bryan likens them to the
various arms of our military – the Army, Navy, Air Force and Marines. In his
analogy he points out that if the country needs to handle a problem in the sea,
calling the Army is likely not the best strategy. Similarly, when looking for
why the immune system is out of control, one needs to understand that there is
more than one ‘branch’, just like in our military.
In other words, a practical example
here, if you feel that you are having a reaction to gluten and you visit your
doctor and he performs an ‘allergy’ test, when the result is negative for
‘wheat’ does that tell you anything? Well, if it was a Scratch Test it tells
you absolutely nothing (more on that in a moment), and if it’s a blood test all
it means is that you don’t have an allergy to wheat. It DOESN”T tell you if you
have celiac disease and it doesn’t tell you if you are gluten sensitive, which is what you wanted to know.
Sadly this happens every day, to who
knows how many suffering individuals. A patient is told that they don’t have an
allergy when they wanted to know if they were reacting negatively to something
they ate. It is two different questions! You contacted the Army when it was a
Air Force problem – see how that analogy works?
To be precise, immunologically
speaking, an allergy creates an IgE response (an immediate, fast and sometimes
life-threatening response – think peanut allergies), while a sensitivity
creates an IgA, IgG or IgM response (a delayed response that can take anywhere
from days to weeks to develop).
You need to ask the body the right
question to get the right answer. And sometimes you may need to ask that
question in a few different ways to truly get the correct answer.
Scratch Tests are NOT Accurate
for Food Reactions
Let’s get back to the scratch test
(skin test) remark I made earlier: The scratch test has been around for 120
years. It is mostly accurate, but not for food reactions. Use it only for
inhalant type allergies – mold, plants, etc. For true allergy food results, use
blood. Please spread the word on this one; too many allergists, who are set in
their ways, convince their patients that these tests are accurate for food
reactions when they are not.
It’s not normal to react negatively
to a food. But when it does happen, the immune response occurs in the gut and
the specific piece of the immune system reacting is called IgA (think Army).
What should occur is that IgA destroys the offending food and ensures that it
is excreted without ever entering the bloodstream from the gut. Unfortunately,
when an offending food(s) continues to be ingested, the site of the battle with
IgA is on the lining of the small intestine. The inflammation that occurs as a
result of that battle causes the tight junctions between the cells to open up,
creating a leaky gut.
Now we have trouble, because the
offending food is no longer contained within the confines of the gut. The leaky
gut allows it to escape out into the bloodstream where it can come in contact
with other parts of the immune system – think Navy and Marines. More correctly
named IgG and IgM. When the immune system of the bloodstream gets involved we
now can enter the arena of autoimmune disease.
Why?
How Autoimmune Disease Develops
The ‘bad guy’ (let’s say gluten) gets
out into the blood and the immune system reacts. The combination of the ‘bad
guy’ and IgG or IgM in the bloodstream initiates something called the
‘complement cascade’ which binds itself to the aforementioned duo. This complex
that is now formed is, according to Dr Vodjani, the MOST pathogenic (meaning
disease causing) and inflammatory (also leading to disease) molecule in the
human body. This is profound. Just read that prior sentence again – “the MOST
pathogenic and inflammatory molecule in the human body”.
[And by the way, an ‘ah hah’ moment
for me came when Dr Vodjani said that the ‘lag time’ between eating a food and
having a reaction in the bloodstream could be as long as 1 to 2 weeks! I had
always thought more in the range of 4 days. So that was a learning pearl for
myself.]
This complement is the trigger for
autoimmune disease. The immune system ‘sees’ the bad guy (e.g. gluten, dairy,
etc) but sadly the bad guy ‘looks’ a lot like cells the thyroid, or joints or
brain. This results is a confusion, and the immune system begins to attack the
cells of the body because they ‘looked like’ the bad guy.
We Have More Control Over
Autoimmune Than You’d Think
Fortunately, autoimmune disease takes
many years to develop. I say fortunately because the best time to stop it is
before it has developed into full-blown autoimmune disease. Dr Vodjani calls it
autoimmune ‘reactivity’, this early stage.
How do we stop it?
We simply remove the initiator or
trigger from the environment – which in many cases is gluten. But regardless of
what the trigger is, you must remove it and you must remove it permanently.
Does this work? I say ‘yes’, but so does Dr Vodjani and Dr O’Bryan. Dr O’Bryan
mentioned that not only does removing the trigger reverse autoimmune disease in
its early ‘reactive’ stage, but it also has been seen to reverse it in its
active full-blown stage. We too have seen that here in our medical and clinical nutrition departments at HealthNOW.
The 64 million dollar question is:
How do we identify the trigger? It’s not hard actually. We have great tests at
our disposal.
Follow These Steps
Here’s all we need to do to prevent
and detect many autoimmune diseases:
1) Isolate triggers to the immune system. This involves testing.
Remember ALL the armed forces… When we test here at
HealthNOW we use comprehensive blood tests that look at immune system reactions
across the board, not just IgE or IgA.
2) Realize that gluten isn’t the only potential food trigger, so
look for others. There is an excellent cross-reactive foods blood test that
looks at many food triggers.
3) Find out if you are already in the autoimmune reactivity zone—meaning early changes have already occurred that will lead to autoimmune
disease. How? We have a blood test for this too. I’ll warn you that this is a
newer test on the market and ‘new’ often means pricey and this one is, but
that’s its only downside. Otherwise it’s brilliant – how wonderful to see early
autoimmune tendencies before they become full-blown disease.
4) Prevent further triggers from assaulting the immune system by
healing the leaky gut. Wondering if you have a leaky gut? Yes, we have a test
for that. But we often ‘save’ that test for later on in care to determine if we
have successfully healed the gut. Often times doing it early on in care can be
a waste of funds when it’s pretty obvious someone is suffering from a leaky
gut.
5) Get ready to be disciplined! One thing Dr Vodjani made perfectly
clear that I completely agree with, and you’ve heard me say it before – Cheating
is a no-no. Eliminating these triggers must be a zero tolerance policy.
A Little Message to Dietary
Cheaters…
By the way, have you ever cheated and
not ‘felt’ it and then thought maybe a little cheating was okay? Dr Vodjani
explained why that occurs. If you used to get headaches let’s say when you ate
gluten and these headaches went away when you embarked on a gluten-free diet,
cheating, either intentionally or inadvertently, doesn’t necessarily mean that
you’ll again experience headaches. Better for you if it did, or at least if
some symptom occurred that caused you some pain and discomfort, because then
you’d be less inclined to cheat. Sadly, for many people their ‘reaction’ is a
silent one. Gluten can destroy your brain cells, as an example, and you can’t
feel that happening. Gluten can cause a lot of destruction inside your better
that you are unable to feel until it’s too late and you have a serious disease.
As Dr O’Bryan put it, Alzheimer’s
isn’t a disease of 50 and 60 year olds. It begins in the 20s and 30s; it just
takes 30 years or so of brain cells being destroyed before you manifest overt
symptoms of the disease and finally receive a diagnosis.
The key is that we don’t want to wait
for the diagnosis, we want to be pro-active. As we talked about earlier,
autoimmune disease is the third leading cause of death and its
incidence is increasing dramatically every year. We know that the trigger is
environmental and we now understand how to isolate these triggers.
Finding the Triggers Is the
Real Key to Prevention and Treatment
That’s pretty exciting actually. It
would be a truly wonderful thing to reverse this disease incidence. Are you
thinking that it’s all genetic? Remember, having the genes for a disease
doesn’t mean that you’ll manifest it… thankfully. Having the genes doesn’t
require you to develop a specific disease, it simply means that you are
predisposed.
Forty percent of the population has
the genes for celiac disease. While the incidence of the disease is on the
rise, it’s not forty percent. So don’t ‘fall for’ the idea that it’s all
genetics, it isn’t. And that isn’t solely my opinion, again I have very good
company amongst world renowned researchers, such as Dr Vodjani and Dr Fasano.
The takeaway from the interview and
the one I’d like to impart is that we have at our disposal the ability to make
great inroads in detecting, preventing and treating autoimmune disease,
something our planet is in great need of – certainly something our country is
in great need of.
I hope you found this informative. The
human immune system is an amazing but complex system. I endeavored to simplify
it better understanding of how autoimmune disease develops.
Let me know if you have any
questions. If you are unhappy with the state of your health, we’d love to help
you. Consider contacting us for a FREE Health Analysis. As a Destination Clinic we treat patients from across
the country and internationally. You don’t need to live locally to us to
receive assistance. We are here to help!
Visit us at www.RootCauseMedicalClinic.com. If you have questions or need any help, I’m here for you! Call 408-733-0400.
I look forward to hearing from you.
To your good health,
Dr Vikki Petersen, DC, CCN, CFMP
IFM Certified Practitioner
Founder of Root Cause Medical Clinic
Co-author of “The Gluten Effect”
Author of the eBook: “Gluten Intolerance – What You Don’t Know May Be Killing You!”