Saturday, January 24, 2009

Interpreting Lab Work

Gluten sensitive patients not only have to do their own research regarding their symptoms but they have to self-diagnose and sometimes are forced to interpret their own lab tests!

I just received the following question:

A lady in my group has the following blood work and I need help with

Tissue Transglutaminase AB is 1.2
Endomysial Antibody is Negative
Gliadin IgA is 1
Gliadin IgG is 1
IgA (Immunoglobulin A) is 152

What does this last one mean? Is that a positive reading?

She had been previously diagnosed a few years ago with DH [dermatitis herpetiformis], but the doctor never told her about the GF [gluten-free] diet, so it was just forgotten. Fast forward a few years and now she was diagnosed with MS [multiple sclerosis]. The doctor at the Cleveland Clinic told her she should go on a GF diet because she probably also has celiac.

She met with me to learn about the GF diet. I suggested she get tested
for celiac first, which she did. Soon after she was tested and read the
information I gave her, she read about the DH and then mentioned she
had already been diagnosed with that. The diet is helping, but she would like to
know the meaning of her blood work. It looks to be negative except for the
IgA, but I don't know what the normal range is for that test.

And with DH, can you test negative via regular blood testing? According to
Dr. Green, you can, but I was wondering if anyone has come across this.
She is trying to understand all this and I want to give her the correct information.

Thanks everyone,

Mansfield, OH

What a sad story. I would like to say it’s unique and uncommon but unfortunately quite the opposite is true. The lack of understanding of the damage gluten sensitivity can cause is staggering.

Here’s a woman who several years ago was diagnosed with dermatitis herpetiformis, a very uncomfortable, unsightly skin condition for which the ONLY known treatment IS a gluten-free diet and she is never told about it. Adding insult to injury the gluten she continued to eat may very well be responsible for the autoimmune, degenerative nerve disease she is now diagnosed with, multiple sclerosis.

To answer the question posed regarding lab tests, let’s take them one at a time. First I’d like to mention that if you want accurate data from a doctor regarding a lab result long distance, don’t just include the result itself but also the reference range of the test. Labs differ in this regard and a result is only as valuable as the reference range is also included.

The data below comes from our book, The Gluten Effect – available February 13, 2009.

Anti-tissue Transglutaminase Antibodies - Anti-tissue Transglutaminase Antibodies (tTG antibodies) are auto-antibodies directed against “self” tissue. After gliadin crosses the intestinal lining, a special enzyme called tissue transglutaminase binds to gliadin and takes off a portion of the protein. This portion is called glutamine. tTG antibodies are antibodies that are directed against the complex of gliadin attached to the tissue transglutaminase enzyme. tTG antibodies are 90 percent accurate in Celiac disease because they represent immune system attack at the level of the intestinal lining. Gluten sensitivity that involves minor intestinal injury or no villous atrophy will be less likely detected by tTG antibodies. Therefore, tTG antibodies correlate best with villous atrophy as several studies have supported, and a negative tTG antibody test (or EM antibody test for that matter) does not rule out gluten sensitivity when intestinal involvement is minimal or absent.

Anti-Endomysial Antibodies - Anti-Endomysial Antibodies (EM antibodies) are auto-antibodies. Gliadin is a gluten protein so therefore when the immune system attacks it, is not attacking “self” tissues but instead a foreign food protein. In contrast, as gliadin is absorbed through the intestinal lining, it attaches to the smooth muscle cells of the intestinal wall. EM antibodies are directed against proteins of these smooth muscle cells, and therefore EM antibodies are directed against “self” tissue. This defines them as auto-antibodies.Because EM antibodies attack the smooth muscle of the small intestine, these antibodies correlate better with damage to the intestine wall. Studies have supported an accuracy rate of approximately 90 percent for Celiac disease. Actually in one study, EM antibodies were present in 100 percent of individuals when total villous atrophy was present. However, EM antibodies are ineffective in detecting individuals with silent or subclinical gluten sensitivity. If minor involvement of the intestinal lining occurs or if no intestinal involvement is present, EM antibodies are much less accurate.As with Anti-Gliadin Antibodies, EM antibody testing should evaluate IgG and IgA forms of antibodies. If a gluten sensitive patient is IgA deficient, IgA EM antibodies may be falsely negative even for Celiac disease.

Anti-Gliadin Antibodies - Gliadin is the protein component of gluten that triggers the immune reactions in sensitive people, and therefore many people with gluten sensitivity have antibodies to this protein. Testing for anti-gliadin antibodies (AGA) is a simple blood test, but studies have shown that it is less sensitive for detecting Celiac disease compared to other antibodies. The confusion is that the ability of AGA to detect gluten intolerance has been defined in conjunction with a positive intestinal biopsy. While this may be a standard for Celiac disease, we now know that this is an inaccurate standard for gluten sensitivity. In fact, AGA may be the best current diagnostic test when considering all gluten related disorders. In testing for AGA, antibodies of both the IgG and IgA classes are checked since low total levels of IgA may be present. If a person has low total IgA levels, antibody tests for IgA may be falsely negative.

Total Serum IgA Level - Low total levels of IgA antibodies are rarely found in the normal population with one out of every six hundred people having this condition, but in gluten sensitivity, low IgA levels are more common. This reflects the increased IgA antibody production in the intestine to fight off gluten as it attempts to enter our bodies. If a low level of IgA is present, then certainly IgG varieties of the antibody tests described above will be more accurate in diagnosing gluten related conditions. In general, total IgA levels are not ordered often since IgG antibody tests are usually ordered concurrently. Therefore, defining a low IgA level adds little information in making a diagnosis. There is a general theory however that a lower IgA level suggests greater inflammation of the intestinal lining and greater chronicity of disease. A low IgA level may provide some insight into duration of disease.

A high serum IgA level as seen in the above test is likely indicating an infection. Increased serum IgA is common in skin, gut, respiratory and renal infections. We know this patient has DH so secondary skin infections do make sense.

The reader also asks if blood tests can be negative with DH. Yes they can. Also remember that even those diagnosed with celiac disease via biopsy show negative blood results 15% of the time.
That’s why the moral of the story at this time is to evaluate how you feel when you eat 100% gluten-free for a couple of months. Until we have highly sensitive tests we can rely on to accurately diagnose gluten sensitivity, diagnosing will involve “building a case” by pulling together many pieces of information about the patient including symptoms, response to a gluten-free diet, lab tests, genetic history, presence of intestinal infections, etc.

This leads us to explain some things about this particular patient. She has known DH which is solely due to gluten intolerance, yet it can be present with negative blood tests. Does that make the diagnosis or need for a gluten-free diet in question? Not at all. She is now diagnosed with MS. We know that, second to the digestive tract, the most common system to be affected by gluten is the nervous system with autoimmune diseases occurring at a very high rate. Does the negative test ensure that gluten had nothing to do with the development of MS? No, it doesn’t. We’d need to know a lot more about this patient (which by the way is the most difficult part of hearing from readers long distance – I want more data.) but I wouldn’t be surprised to find other factors which point to gluten as the culprit.

To Your Good Health!

Dr Vikki Petersen


Anonymous said...

Was told im not celiac....But I feel horrible. What do you think?

Found my old results:
Gliadin Antibody IGG 31 High Range <11
Gliadin Antibody IGA 6 Range <6

Reticulin igg ab <1:10 Range <1:10
Reticulin IGA AB <1:10 Range <1:10
Tissue Transglut. IGA <3 Range <5

Then last year Everything the same but Gliadin IgG 23.4 High Range <10

What does it mean that eveything is normal BUT the Gliadin IgG?

The HealthNOW Doctors said...

I cannot diagnose you over the internet, of course, but I can tell you that the test the was performed was looking for indicators of both celiac disease and gluten sensitivity. That's good.

And while the celiac indicators are negative, gliadin antibody testing, whether IgG or IgA, is an indicator of gluten sensitivity.

I would be happy to assist you with more specific advice. Just give us a call for a free health analysis. Call 408-733-0400.

To your good health,
Dr Vikki

Anonymous said...

My daughter recently had the following blood work results. These were ordered by General Doctor as she was experiencing diarehha. No other major symptoms. The results were/are:
Gluten Sensitivity Panel
Endomysial Ab IgA negative

Tissue Transglutaminase Antibody
t Transglutaminase Ab IgA 23* 0-20 EU/ml

She was advised that she is allergic to all glutens.
Is that correct?

She has been referred for an ?endoscopic examination with a specialist.

Also does being a vegan contribute to this?

Please let us know about the results.

Thanks very much
: )

The HealthNOW Doctors said...


A positive tTG test is indicative of celiac disease. You doctor is recommending a biopsy to confirm that diagnosis.

Even if the biopsy comes out negative, there has to be a reason the tissue of your daughter's small intestine is being destroyed.

If the biopsy is positive then there is no argument, of course, but do let me know if any confusion arises should the biopsy be negative.

Do understand that celiac is a genetic disease and being a vegan has absolutely nothing to do with its development. Personally I am pro-vegan, but that's beside the point.

If it critical that your daughter avoid all gluten plus get assistance in healing her gut. Typically general doctors don't excel at that.

Feel free to call me for a free health analysis and we can discuss specifics - 408-733-0400.

Your daughter can enjoy excellent health if the right things are done now. By the way, the rest of the family should be checked also - it is a genetic disease.

Dr Vikki

Patricia V said...

I have been having stomach issues. I went for a blood test and they performed a celiac disease panel. This is the results:
Transglutaminase IgG <15
Transglutaminase IgA 27.3

Gliadin IgG: <15
Gliadin IgA <15

My primary dr. said he thinks I have Celiac Disease (and so does my mother). He wants me to make an appt with a Gastrointerologist. Just by the numbers (after all my research) it looks like Celiac. Transglutaminase is elevated isn't that indicative of Celiac? I am just confused by the might.

Any thoughts?

Patricia V said...

I have been feeling lousy and so my dr did a blood test to check for Celiac since my mother has it. When he called me back he said I need to see a Gastrointerlogist because I probably have Celiac. He sent my my resuls and I am a little confused after doing some research.

These are my results.

Transglutaminase IgG <15
Transglutaminase IgA 27.3

Gliadin IgG <15
Gliadin IgA <15

Using numbers only since you don't know me. Do I have Celiac? I am a little confused when my primary care dr says I may have Celiac.

Any opinions until I see the gastro dr would be great!

Anonymous said...

What are abnormal results? My tests. were tissue Transglutaminase igG
0.15. IgA 0.50 is this celiac??

The HealthNOW Doctors said...

It depends on the lab. There is a normal range. Anything above that would be highly suspicious.

If you want to give me more data I'd be happy to help with further questions.

Dr Vikki

The HealthNOW Doctors said...

Dear Patricia V,
Yes, you are correct. An elevated tTG level IS indicative of celiac disease.

Too often, even positive tests are not acted upon aggressively by clinicians who aren't expert in the area of gluten.

Please consider calling us for a free health analysis. We are here to help! Call 408-733-0400.

Dr Vikki

Anonymous said...

This are my test results:

Gliadin Ab (IGA) 49
units (<20)---[Is it very high? What would be the highest number?]
Gliadin Ab (IGG) 13

>or 20 Antibody detected

Endomysial Ab Scrn: Positive

Those were tests I had for celiac. Doctor told me to go on gluten free diet since tests are positive for celiac disease. But what does it mean that IGG is negative? And IGA 49 confirms celiac?
I didn't have a biopsy performed. I am 4 months on gluten free diet and I am not feeling better. :(

Thank you

The HealthNOW Doctors said...

@ Ada,
It is the positive endomysial test that is causing your doctor to diagnose celiac disease.

The AGA tests, one of which is positive is indicative of gluten intolerance, but doesn't make a distinction between celiac and gluten sensitivity. But with the endomysial positive, that indicates celiac.

Understand that anything positive is positive.

Either you have celiac or you don't. There's no such thing as 'mild celiac' or 'a little celiac'. In other words, whether the number was 21, 31 or 81, it wouldn't matter - the point is that it's positive.

The reason you don't likely feel better is that the secondary effects associated with gluten are not being addressed for you.

That is our specialty and it's not difficult to address. If you'd like help please consider calling us for a free health analysis. Call 408-733-0400 - we are here to help.

Dr Vikki

Anonymous said...

I have a transglutaminase IgG of 34.7 which said 15 is average. The endomysial Iva is negative. Tirer is negative. Immounoglobulin a is 136. Primary said maybe is celiac. Gastronomic said both could be false positives need to do endoscopy. I have to go to specialist but why is level high and do u think this is celiac. Any other blood test that could help diagnose with endoscopy. Thank you

The HealthNOW Doctors said...

The positive tTG is quite suspicious of celiac disease. I don't know what your symptoms are but a biopsy is a way to confirm.
With that said, do understand that biopsies are not perfect and it is possible to have celiac disease with a negative biopsy.
If you'd like a free health analysis so that I can better understand your health status, you are welcome to do so. Call 408-761-3900.
It is very important that you find out conclusively if a gluten-free diet is something that you need to implement.
I'm happy to assist you.

Anonymous said...

My results are:
Transglutaminase Ab (Iga) <3
IGA SERUM 52 low
c-reactive is high
speckled 1:80
Feel awlful, weight gain, have high blood pressure,imflammation and pain.

The HealthNOW Doctors said...

Dear Anonymous,
When you're general IgA results are low, any test utilizing that immunoglobin will be false. Therefore we cannot tell whether you have a positive tTG or not. It's too bad that the lab did not also measure IgG. Most labs these days do that for this exact reason.
The high C-reactive protein shows inflammation, so it is important to figure out where that it coming from.
You can contact us for a free health analysis (408-733-0400) if you'd like.
Dr Vikki

Anonymous said...


My mother has celiac disease and I been having stomach pain a day or two after eating wheat product. I was tested and the results are confusing;

IMMUNOGLOBULIN A 248 mg/dL [46-287]

Can you advise if this may be false negative? Why is the IgA so low?


The HealthNOW Doctors said...

It's not actually confusing, just potentially incomplete.
The tTG is negative and the IgA is normal too. While one could say this is a negative celiac test, it really should include a blood test for anti-gliadin antibodies and deaminated giadin - 2 more blood tests used in a celiac panel.
It is unfortunate that we don't have one perfect test, but we don't. Another great test, if you're still consuming gluten is Cyrex Labs comprehensive profile for both celiac and gluten sensitivity.
You obviously feel poorly after eating gluten, now we just need to find out if you're gluten sensitive or celiac. A genetic test is another option.
Hopefully I'm not confusing you!
If you'd like a free health analysis where we could speak more personally, consider calling us at 408-733-0400.
Dr Vikki

Rosanne Zimmerman said...

Hello Dr. Vikki

My daughter is gluten sensitive and was having general ill health and CNS problems ie. muscle ticks. Gluten free two month and lost 20lbs and said she did not know she could have so much energy. Muscle ticks are minute now. Anyways before going gluten free we did have the celiac test done. Gliadin AB: IgA was <3(ref 0-20), Gliandin AB: IgG was 5(ref0-20) and Tissue Transglutaminase was 3(ref 0-20). Now I get these numbers are below the ref range for celiac and I know due to a gluten free diet she is sensitive or intolerant. I am just trying to interpret her numbers. Her neurologist said the if she did not have gluten intolerance then she would not have antibodies. Is this true? Would a healthy person without gluten problems have 0 antibodies. Does the indication of any antibodies indicate gluten sensitivity? I am reading your wonderful book and just trying to understand all of this as I just had my testing done as well. I was gluten free before having the test done so may not be so accurate but read that as long as one is not gluten free more than 6 months they can still have blood test do to antibodies still being produced. Is that true? Just want to know how to interpret my tests when they come back. This is so complex. I recommend your book to everyone. Very easy to read on such as complex issue.

Anonymous said...

I recently had blood work done because my dr suspects I have celiac. Here are my blood work results:


IMMUNOGLOBULIN A 508 (Standard Range is 81-463 mg/dL)


My doctor said she thinks it's positive for celiac but suggested I follow up with a GI doctor.

I can see by IGA is above standard range, but what do the other numbers mean? They both seem to indicate that there is no antibody detected - does that mean it is positive for celiac?

Any thoughts would be appreciated!

Anonymous said...

I recently had blood work done because my dr suspects I have celiac. Here are my blood work results:


IMMUNOGLOBULIN A 508 (Standard Range is 81-463 mg/dL)


My doctor said she thinks it's positive for celiac but suggested I follow up with a GI doctor.

I can see by IGA is above standard range, but what do the other numbers mean? They both seem to indicate that there is no antibody detected - does that mean it is positive for celiac?

Any thoughts would be appreciated!

The HealthNOW Doctors said...

The tTG is definitely negative at 1, but depending on the lab used, I don't know if the AGA at 11 is considered to be positive. It would be for my lab but different labs have different reference ranges.

The IgA is a bit high indicating some immune system stress, but unclear as to why at this point.

So, I need more data. Also, realize that these tests aren't perfect so a negative test could still mean a positive gluten intolerance.

I know that's a little frustrating, but we can figure it out. If you'd like assistance please consider calling us for a free health analysis - 408-733-0400.

yasmin said...

my 4 yearold daughter was diagonised for celiac disease 1 year before.she was confirmed after a biopsy. Since then she eats gluten freefood.After 6 mnths her endomysium Abs (IgA)become has dropped down from >200 which was at the time of after an year her level is 13.47.i wud like to know y it has increased?

The HealthNOW Doctors said...

Dear Yasmin,
Each lab has different reference ranges. Is the '13' above the reference range? In other words was 5 negative and is the 13 positive?

If the 13 is still below the reference range, I wouldn't be concerned. As long as the number is negative, your daughter is doing well.

If the 13 is positive, then I would be looking at contamination, hidden gluten and potentially cross-reactive food reactions.

Consider contacting us for a free health analysis if you would like some assistance figuring it out. Call 408-733-0400.

Dr Vikki

Anonymous said...

My Tissue Transglutamianse IgA serum result is 23.05, range is <18. does it mean i have celiac disease?

Anonymous said...

My Tissue Transglutamianse IgA result is 23.05, range is <18. does it mean i have celiac disease?

The HealthNOW Doctors said...

It is quite suspicious. What does your doctor say? Do you have symptoms of celiac disease? Can you get a genetic test? Does celiac disease run in your family?

As you can see I have many questions. Please feel free to write back.

Anonymous said...

i would so much appreciate help with labs.pediatrician ran celiac panels and kids were under 19(=negative) for tTG igG and tTG IgA, so the lab did not perform the endomys igA. they tested under 19(=negative) for dgp IgG and igA, too.i am still worried because i have two dq8's, out of range occludin/zonulin IgM and lipopolysaccarides IgM. my transglutaminase-6 IgG is 2.29(should be below 1.5).can my kids still have transglutaminase-6 damage from other proteins that they need tested for?

anonymous said...

I asked for gluten blood tests at a private lab on my own (without a doctor) because I'm living overseas right now. This was after reading symptoms online. Can someone help me interpret the results?

IgA 1,7
IgG 0,9
Anti-IgA 19,4
Anti-IgG 3,0


The HealthNOW Doctors said...

Dear Anonymous,
Labs have reference ranges - meaning a range that they consider normal. You'd need to include that information for me.

Was the IgA for tTG, endomysial, anti-gliadin? That seems to be missing as well.

You need to look carefully at the report that you received and include all the data.

Dr Vikki

Anonymous said...

thank you for your help.
Yes it has references which I found difficult to understand. Here they are with my numbers there also:

IgA 1,7 antibodies to tissue transglutaminase
negative: 0,0-10,0 U/ml positive: => 10,0 U/ml

IgG 0,9 antibodies to tissue transglutaminase
negative: 0,0-10,0 U/ml positive: => 10,0 U/ml

Anti-gliadin IgA 19,4
negative: 0,0-12,0 U/ml positive: => 12,0 U/ml

Anti-Gliadin IgG 3,0
negative: 0,0-12,0 U/ml positive: => 12,0 U/ml

Anonymous said...

Apologies if you receive this 2x-hadn't logged on.
Thank you for helping! Here is is again with the references:

1,7 IgA antibodies to tissue transglutaminase
Negative 0,0-10,0 U/ml Positive >/= 10,0- U/ml

0,9 IgG antibodies to tissue transglutaminase
Negative 0,0-10,0 U/ml Positive >/= 10,0- U/ml

19,4 Anti-gliadin IgA
Negative 0,0-12,0 U/ml Positive >/= 12,0- U/ml

3,0 Anti-gliadin IgG
Negative 0,0-12,0 U/ml Positive >/= 12,0- U/ml

Elisa (test name?) written under numbers

The HealthNOW Doctors said...

The positive result is the AGA IgA. This test being positive is consistent with gluten sensitivity, although it is possible to be positive in celiac disease. With the other results being negative the more likely disorder is gluten sensitivity but this would need to be corroborated with other information.
I cannot diagnose you over the internet, of course, but if you'd like some assistance, consider contacting us for a free health analysis - call 408-733-0400.
We are here to help!

The HealthNOW Doctors said...

Dear Anonymous asking about your children. Yes, they could have tTG-6 possibly. Have you done genetic testing on the children.
That might be a good place to go next.
If you need assistance, consider calling us for a free health analysis - 408-733-0400. We are here to help!

Anonymous said...

Hi - I think I'm dealing with the opposite problem of most people here. My lab results seem to say that, if anything, I only have a mild gluten allergy yet I have a doctor saying I can never eat wheat, gluten or dairy again for the rest of my life (the last shows in very low positive - just .06 over the Equivocal range into 'Out of Range' - and Equivocal ranges on a Cyrex lab).

I have LabCorp tests:

Deamidated Gliadin Abs, IgA=4 units (1-19 Negative; 20-30 Weak Positive; >30 Moderate to Strong Positive)

Deamidated Gliadin Abs, IgG=2 units (1-19 Negative; 20-30 Weak Positive; >30 Moderate to Strong Positive)

t-Transglutaminase (tTG) IgA = <2 U/ml (0-3 = Negative; 4-10 Weak Positive; >10 Positive)

t-Transglutaminase (tTG) IgG = <2 U/ml (0-5 = Negative; 6-9 Weak Positive; >9 Positive)

Endomysial Antibiody IgA Negative

Immunoglobulin A, Qn, Serum = 222 mg/dl (91-414 Limit range)

Is this doctor trying to hit me with a "Every problem is Gluten sensitivity or Celiacs!" hammer when that's not my problem? (I'm also fighting Lymes Disease.)

The HealthNOW Doctors said...

Dear Anonymous,
I understand your confusion; let me explain. The Lab Corp results you cite are for celiac disease and those are negative.

The Cyrex test you received, based on the value you gave me, is stating positive for gluten sensitivity. I know Cyrex quite well and they feel that anything in the 'equivocal' range, let alone the 'positive' one is cause for serious consideration. In other words, even if you hadn't just barely crossed out of equivocal into out of range, your doctor would still likely have recommended you go gluten-free and I don't disagree.

Have you tried it? Do you feel better on a gluten-free diet? These too are valid questions.

It's hard to give you more information without a conversation. If you'd like a free health analysis, consider calling us at 408-733-0400.

I hope that helped!

Dr Vikki

Anonymous said...

Thanks, Dr. Vikki!

I've asked for Cyrex Array 3 to be done (that was never done) and I think that will clear things up for me. Your explanation helps as well. So, not Celiac but mild gluten crossover allergies given the following:

- Cow's Milk 1.11 (Noted as Equiv; - range=0.1-1.3)
- Casein 1.26 (range=0.1-1.2)
- Casomorphin listed as negative at 0.58 even though the range=0.2-1.6???? What the heck?? Why is this not listed as Equiv?)
- Milk Butyrophilin 1.15 (Noted as Equiv; range=0.1-1.3)
- Whey Protein 1.35 (range=0.1-1.3)
- Chocolate (milk) 1.01 (Noted as Equiv; range=0.1-1.4 - thank goodness I like dark chocolate which I was told is ok)
- Coffee 2.30 (range=0.2-1.2 - was told this is only for instant coffee but I rarely have more than a sip of good quality coffee a month so no big loss)
- Sesame 2.79 (range=0.1-1.3)

Oddly, while Sesame is my strongest response, I'm told I can not have any for 6 months and then I can try adding it back in. Dairy response numbers are so much lower and yet Sesame is going to be ok with me in 6 months vs. dairy is something I'm never again supposed to have?? That and the value vs. the range of Casomorph make no sense to me.

I've seen some Cyrex array 4 lab results online where 80% or more are listed as problems so I'm told I'm lucky. That being said, I did great on SCD which includes butter, hard cheeses, and homemade yogurt that's been fermented 30+ hours. I stopped living that way 100% of the time because it was a) expensive, b) inconvenient, and c) time consuming.

While I absolutely do better keeping dairy (and even wheat) in moderation, I certainly don't wreck myself when I have the occasional ice cream or grain product. In fact, when I am regularly working out, I don't seem to have any problems with such things at all. Further, I don't have a problem with these foods when I'm overseas (but, for grain products, that's more to do with an inability to use folic acid and being MTHFR C677T homozygous - another kettle of fish. Thyroid is mixed in there too as I hurt when I eat these things if I'm not on T3/T4 but, again, only in the United States - I don't have a thyroid issue while in 4 other countries I've been for work.

Annie Garrie said...

Hi, both my sons were told to go on gluten free diet after one of the four tests had come back pos. I don't know what test came back pos for my oldest, but I am going to get to the bottom of that soon. My other sons IgG was 56. What exactly does this mean? Everything else is normal range. I have been reading up and it scares me that he may not have celiac, but maybe a different autoimmune disease. I have him on a gf diet for 3 months now, and not sure what to do next to make sure this is all we need to do. Please help

Annie Garrie said...

Hi, I just was told my sons IgG was what came back pos on his Celiac panel. His IgG was 56, and I'm not sure what exactly that means. I was told put him on a gf diet. I did more research online and am now wondering if it's possible with it being so high that he may have a different autoimmune disease. What are your thoughts?

The HealthNOW Doctors said...

Hello Annie,
I'm sorry for the delay in getting back to you. We get a lot of traffic and every once in a while an email gets missed, I apologize.

I would need more information in order to answer your question. IgG is a part of the immune system, not the name of the test. There would be more to it. Also a "56" doesn't mean much without the reference range.

I know as a parent how frustrating it can be to not fully understand or get answers as regards your children's health.

I would like to offer you a free health analysis (just call 408-733-0400) and then we can talk and I can better assist you and your children.

I look forward to hearing from you.

The HealthNOW Doctors said...

Hello again Annie,
Well I no sooner post my last comment and another question appears from you that did clarify things quite a bit.

So it was a celiac test and "56" was quite high - got it. There are other criteria to use to determine if it's truly celiac and do know that a biopsy doesn't have to be one of them as it in quite invasive for a child.

As I mentioned earlier, I'd be happy to discuss it further with you over the phone and I can give you specific ideas of how best to proceed.

The HealthNOW Doctors said...

I cannot give medical advice to you over the internet but speaking generally, I can give you some ideas. The positive amongst these is the anti-gliadin antibody, IgA. While not conclusive, this test is often used as an indicator for gluten sensitivity.
I'm assuming you were eating gluten at the time of the test- correct?

The best next step I could suggest is to consider contacting us for a free health analysis - call 408-733-0400. That way we could speak directly and I could get more information.

I wouldn't ignore these results. I would behoove you and your health to find a clinician who is an expert in this field if you choose not to contact us.

Good luck!

The HealthNOW Doctors said...

@Roseanne- Gluten tests aren't really accurate if you're perfectly off it much beyond 3 weeks after elimination.

As regards your daughter, did the test her total IgA. I'm wondering if the total was low - that would skew her tests. Low IgA is quite common in those w/ gluten issues.

I'm glad you enjoy the book!

If you or your daughter needs some assistance, consider contacting us for a free health analysis - call 408-733-0400. Then we can speak and create the best approach to optimize your and her health.

We are here to help!

Anonymous said...

I just received results from a celiac panel and am having a hard time interpreting the results based on the research I've done.

gliadin antibody iga 4 (less than 20 is normal)
gliadin antibody igg 3 (less than 20 is normal)

ttg iga 5 (less than 20 is normal)
ttg igg 4 (less than 20 is normal)

According to this report everything is normal...but in some of my research it looks like Iga levels less than 7 indicate another problem. Am I misunderstanding my research?

The HealthNOW Doctors said...

Hello Anonymous,
What you are thinking of is that if the total IgA is low then tests measuring IgA such as the tTG and AGA can be falsely negative.

This is true. It doesn't appear that they tested your total IgA. At least you don't mention it.

So your tests could very well be negative, but without the total IgA number we can't know for sure.

Let me know if you need any assistance.

Anonymous said...

Hi please can you help decipher my blood test results.
Tissue transglutaminase IgA level =1.8 kU/L (<5.0) and IgM = 0.76 g/L and IgA= 2.76 g /l and IgG =14.2 g /L.

I was told to go on gluten free diet the month before.
Doctor said my previous Tissue Transglutaminase IgA level was 17.9 kU/L. So its come down greatly to 1.8. I'm still confused as she fully explain my results. Please can you help? Thanks.

Anonymous said...

Hello I just received my blood results
Tissue Transglutiminase, 0.4

Tissue Transglutimnase, IgG <0.6

Gldn Antibody,IgA(Deamid) 1.0

Gldn Antibody,IgG(Deamid) <0.4

Anonymous said...

Tissue Transglutiminase, IgA <7 IU/mL 0.4
Tissue Transglutimnase, IgG <7 IU/mL <0.6
Gldn Antibody,IgA(Deamid) <7 IU/mL 1.0
Gldn Antibody,IgG(Deamid) <7 IU/mL <0.4

Positive or negative??

Anonymous said...

Tissue Transglutiminase, IgA <7 IU/mL 0.4
Tissue Transglutimnase, IgG <7 IU/mL <0.6
Gldn Antibody,IgA(Deamid) <7 IU/mL 1.0
Gldn Antibody,IgG(Deamid) <7 IU/mL <0.4

The HealthNOW Doctors said...

@ Anonymous who recently posted. All the values you wrote down are negative.
That doesn't necessarily mean you don't have a problem w/ gluten as there are more comprehensive tests, but the ones you cite are negative.

If you're having health difficulties and want to get to the root cause of what's happening, consider contacting us for a free health analysis (call 408-733-0400). We are here to help and treat patients from across the country and internationally.

The HealthNOW Doctors said...

@Anonymous whose doctor stated the tTG level for IgA has come down:
The IgG level is still elevated based on the values you wrote down.

I would be happy to help. My best suggestion is to call us for a free health analysis (call 408-733-0400) so that we can discuss how you're feeling and what you've done thus far.

We are a destination clinic and treat patients from across the country and internationally. We are here to help!

I look forward to hearing from you.

Anonymous said...

Hi. My 3 year old son was just tested for Celiac after 1 mo of diarrhea. His sister has confirmed celiac disease. Two years ago, his screening was totally negative. These are the results we just received:

Quant Serum IgA: 30 (44-189)
Gliadin IgA Ab: 6 (no reference)
Gliadin IgG Ab: 21 (High)
Transglutaminase IgA: <2 (0-3)
Transglutaminase IgG: 6 (0-5)
Endomysial Ab IgA: Negative

Please help! What does this mean?

Amy said...

My 3 year old son was just tested. His older sister has confirmed Celiac. Two years ago, his test was negative. This is now his panel:

Total Serum IgA: 30 (44-189)
Gliadin IgA AB: 6 (No reference)
Gliadin IgG AB: 21 (High)
Transglutaminase IgA AB <2 (0-3)
Translutaminase IgG AB 6 (0-5)
Endomysial AB IgA Negative

Help! What does this mean??

The HealthNOW Doctors said...

Hello Amy,

I understand your confusion. I very much want to help you and your son.

Please consider contacting me at the clinic for a free health analysis - it's no charge and then we can speak. It's a better format than this one to ensure I answer all your questions.

Just call 408-733-0400.

I look forward to hearing from you!

Dr Petersen

Anonymous said...

Here are my test results
Coeliac serology
Deaminated Gliadin Iga 1 U/mL (<15)
Deaminated Gliadin IgG <1 U/mL (<15)
Tissue Transglutaminase IgA <1 (<15)
Tissue Transglutaminase IgG <1 (<15)

Told its a normal result fir a person who eats wheat.

I also have done a simtomax test which indicated positve for coeliac disease and IgA deficient, I am confused. Any comments appreciated thanks

Kamber said...

So I am trying to understand what some tests mean. If there are gliadin antibodies present but not necessarily at the level to be classified as Celiac disease, or if there are transglutaminase antibodies present even if they are not over the levels considered to be celiac, would that mean that there is gluten sensitivity?

Kamber said...

Trying to understand gluten sensitivity. Do you all people have antibodies towards gluten? If labs indicate that there are antibodies present but not at "celiac levels", then would this be classified as gluten sensitivity?


The HealthNOW Doctors said...

Tests have ranges. There is a normal range and above that level a patient is considered "positive" for a certain disease or condition. So if a celiac panel is negative, in the normal range, the patient is told they don't have celiac disease. Similarly if a patient is tested for anti-gliadin antibodies to see if they may have gluten sensitivity, there too is a range of normal and abnormal that would be evaluated.
And, now that I've made it sound so simple, I'd be remiss to not mention that tests aren't perfect and there are ways to "read between the lines" and issues to consider when evaluating labs.

If you are not feeling well and need assistance, consider contacting us for a free health analysis - call 408-733-0400.
We are a destination clinic and treat patients from across the country and internationally.
We are here to help!
I look forward to hearing from you!

The HealthNOW Doctors said...

@ Anonymous w/ test results.
A deficient IgA will skew the results of tests that use it as a yardstick, which many coeliac tests do.
I'm not familiar with the symtomax test, but I do often find deficient IgA in those patients with coeliac or gluten sensitivity, so that part does ring true.
I'd need a bit more information to assist you. Consider contacting us for a free health analysis - call 408-733-0400.
We are a destination clinic and treat patients from across the country and internationally.
We are here to help!
I look forward to hearing from you!

Anonymous said...

Firstly thank you for all your time replying. It's very helpful to be able to read.

My question is more general in nature than related to specific numbers. I am a little confused by the newer dgp igg results. If they are high but all other results are within normal range is it still a strong indicator of celiac only or could it also indicate a gluten intolerance.

I can't seem to find confirmation that positive dgp igg with no other positive results is as much a sign of celiacs on it's own as with other positive bloodwork. Mostly it's mentioned that both dgp igg and iga is positive it's almost surely celiacs, but not what igg by itself indicates. This is with symptoms btw.

The White Family said...

My son was diagnosed with type 1 diabetes 5 years ago and has since had a celiac panel done 3 times. all his test results have come back within the ranges for normal. However, we have found that other members of our family who also did not have abnormal test results feel better when gluten free. My question is about increasing results over time, even if still below range, would this show increasing sensitivity or damage and thus the likelyhood to develop positive test results in the future.
The concerning numbers are Deamidated Gliadin Abs, IgA the range is under 20 for negative. His numbers were 7 in 2010, 8 in 2011, and 10 in 2014.
Also, he has had more uncontrolled sugars over these years which we thought were due to site absorption issues. Wondering whether the absorption problems and out of control blood sugars could be due to gluten sensitivity.

Krystal23 said...

Endomysial Antibody IgA Negative N
t-Transglutaminase (tTG) IgA <2 N
Immunoglobulin A, Qn, Serum 395 mg/dL N
This is my celiac panel results. I'm confused because there is wording saying endomysial has been detected but it's written like this. what does this mean for me?

Ken097981 said...

great info on your site, had a question:

Had a endoscopy and biopsie showing:
"moderate chronic inflamation, fragments of small intestinal mucosa incresed number of intraepithelial lymphocytes (IEL). focal evidence of blunting of villi. suggestive of celiac disease" which is effective MARSH 3.

but bloodwork done was
Tissue transglutaminase IGA <2 (negative)
Tissue transglutaminase IGG 6 A reference range was 6-9 WEAK POSITVE
Endomysial IGA negative

Doc said that this indicates 'No Celiac' because both need to 'react'. This doesnt make sense to me, wouldnt any antibodies, ie the IGG being positive (even weak positive) with biopsy evidence be enough to confirm the Celiac diagnosis.

I realize the next step is to get a total serum IGA to rule out the IGA deficiency potential here (as well as the more in depth cyrex array 3 or similar testing) and a gluten free challenge followed by re-biospy in 6mo.

but i guess my guestion is wouldnt IGG of 6 coupled with visual evidence indicate immune response commensurate with a Celiac diagnosis.

Anonymous said...

Can you help? My six year old son has severe chronic constipation. We tried fiber, water, gets plenty of exercise etc. We were told his lab results were normal but I just received them in the mail and they came back at

IgA 31(L) (Range 33-200)
tTG Ab, IGA, S <1.2 (no range given)

Does this exclude a gluten sensitivity? He had extensive surgery as a newborn, would this alter his results? There is a history of GI problems on his fathers side (IBS, Chrones)

Matt M said...

Hello. My doctor said my numbers are off the chart and I wanted to confirm. Also see why my 1st number is negative -
1. Endomysial Antibody IgA Level is <1.5 - just says negative
2. Tissue Transglutaminase IgA Level is 134 - says anything over 30 is positive
3. Gliadin IgG Antibody Level is 41 - says anything over 30 is positive
4. Gliadin IgA Antibody Level is 116 - says anything over 30 is positive
5. Immunoglobulin A is 1310 - says range is 40 - 350 mg/dl
6. Anti-Mitochondrial Antibody is 11.4 - says anything under 20 is negative
7. Anti-Smooth Muscle Antibody level is 51 (Mod-Stron Positive) - says anything greater than 30 is positive.

Also just to tell you. I am 33. I have Been diagnosed with Celiac Disease (already had a biopsy as well). I also have Anemia and Cirossis of the liver. They also think possible auto-immune hepatitis. Although after my biopsy they said the last one was not consistent with the biopsy. Thank u. Matt M.

Jenn said...

I have had iron deficiency anemia (Hgb 6.9) for several months. I was sent to GI doctor and had an endoscopy and colonoscopy. Colon was normal but duodenal biopsy showed "partial villous atrophy with non-specific malabsorptive pattern". My Celiac Panel was negative X2 (a year apart) but this test:
Allergen Gluten IgG was 11.0 mcg/ml ref = <2
Gliadin IGG - 5 units
Gliadin IGA - 6 units
Immunoglobulin A 175 mg/dl
Tissue Transglutaminase NO antibody detected

So, does this sound consistent with needing a GF diet? My primary care says yes but my GI won't commit. I do have migraines from time to time and occasional bloating and constipation but I'm not sure it is all related.

Omer Inam said...


I have been having upper chest pains and a chronic mild pressing pain in my esophagus for over a year now. I had an endoscopy done last year which showed the following result:

Biopsy result:
1. Mild Chronic non-specific grastritis. Few H-Pylori like organisms. No evidence of metaplasia or malignancy seen.
2. Fragments of small bowel mucosa with an intact villo-glandular architecture. No definite giardia seen.

I was put on Lansoprazole and Itropride HCL which somewhat helped reduce upper chest and esophagus acidity symtoms.

Over 2 months ago, the symptoms got aggravated after which the gastroenterologist asked me to the TTG IGA and IGE test and the following results came out:

Anti-Transglutaminase Iga 13.32 U/ml
Anti-Transglutaminase IGa 3.76 U/ml

Reference range:
Negative < 12 u/ml
Equivocal between 12 to 18 u/ml
Positive > 18 m/ul

After looking at my results, the doctor suspects I have Celiac Disease and in order to reconfirm, i underwent endoscopy yesterday and the biopsy have been taken and I will get the result in a weak to confirm whether I have Celiac Disease or not.

The endoscopy procedure observations were as follows:

1. Esophagus: Z line at 40 cm. Gaping lower esophageal sphincter
2. Stomach: Mild pangastritis erythema
Duedenum: Normal D1. Occassional superficial fissuring of duodenal folds.

My primary concern is the mild presing pain I feel in my esophagus most of the time which is accompanied by upper chest pain.

Sorry for the lengthy message but can you please advise what the above diagnosis mean?


SriK said...

Looks like I have Celiac based on the following:
IGA,SERUM 158 Normal (81-463 range)
(TTG) AB, IGG 14 HIGH (Normal would be <6)
Does the last line mean I definitely have Celiac? If yes, how high is this value?
Also, can (TTG) AB IGG be high and Gliadin Deamidated AB, IGG normal in Celiac cases?

I would greatly appreciate a quick opinion.

Thank you.

The HealthNOW Doctors said...

Yes, the tTG is high and that is an indicator of celiac disease. I don't know your symptoms nor history and of course it's not legal to diagnose over the internet, but such a finding does need to be followed up to determine the cause. Other than celiac disease, such a finding is common in patients who have other autoimmune conditions, such as chronic liver disease, Type 1 Diabetes, Crohn’s Disease or thyroiditis.

If you'd like assistance in determining what to do next to improve your health, consider contacting us for a FREE consultation - we're here to help!

Dr Petersen

The HealthNOW Doctors said...

@anonymous with 3 year old son: First let me apologize for the delay in writing back to you. For some reason your comment slipped through the list given to me and I only just saw it.

There are two positive values: The IgG for gliadin Ab and the IgG for tTG. The positive tTG is a celiac market, the gliadin Ab can be seen positive in celiac as well as non-celiac gluten sensitivity.

I cannot diagnose over the internet but I am more than happy to discuss this with you in person over the phone where I can get some more information regarding your son's health. Consider contacting us for a FREE consultation _ call 408-733-0400.

If that is not of interest I would like to say that I feel it is important to not ignore these values and please do find a clinician who can move you forward to improving your son's health and avoiding the many secondary health effects gluten can create.

Dr Petersen

The HealthNOW Doctors said...

@Omar Inam: I'm sorry for the delay in getting back with you. I hope you are doing better. If you still need assistance consider contacting us for a FREE consultation - call 408-733-0400.

Hopefully you've found a clinician who is getting to the root cause of the inflammation in your esophagus and small intestine. If not, please feel free to contact us as mentioned above.

I look forward to hearing from you!

The HealthNOW Doctors said...

@Jenn: sorry for the delay in getting back with you. The celiac test is negative but the gluten sensitivity markers are showing positive. These results would be consistent with what your one doctor recommends: a gluten-free diet.

Also ensure your doctor is familiar with the steps to take to heal the small intestine and normalize the immune system after you have embarked on a gluten-free diet. There is more to do than only remove gluten. The good news is that it's a natural program.

If you need assistance consider contacting us for a FREE consultation - call 408-733-0400. We're here to help!

The HealthNOW Doctors said...

@Matt: Hello and sorry for the delay in answering this. The results you shared are not only consistent with celiac but also, it appears, additional autoimmune diseases. I don't know where you live but I would like to assist you in ensuring you have a clinician who can work with you properly to really heal what is occurring, most especially the GI tract, liver and immune system.

Consider contacting us for a FREE consultation and we can discuss this further. Call 408-733-0400.

The HealthNOW Doctors said...

@ anonymous w/ 6 year old son: The IgA being low is indicative of an immune system that is being overwhelmed by something. What needs to be determined. I didn't understand what you wrote as the value of the tTG test: you wrote: "tTG Ab, IGA, S <1.2 (no range given" Was the "S" a "5"??

I would be happy to assist and the good news is that children are rather easy to fix, despite his rough early start with surgery.

Consider contacting us for a FREE consultation and we can discuss it further. Call 408-733-0400.

The HealthNOW Doctors said...

@Krystal23: sorry for the delay in getting back to you. Based on what you wrote here, those values are all negative. I don't know anything about your health history nor how you feel but the panel you share is specifically for celiac, it doesn't rule out non-celiac gluten sensitivity.

If you'd like to discuss it further and see if we can assist, consider contacting us for a FREE consultation - call 408-733-0400. We're here to help!

The HealthNOW Doctors said...

@Ken097981: sorry for the delay in getting back w/ you. I agree that "any" positive immune reaction should be taken as highly suspicious and along with the biopsy results,it might be prudent to remove gluten from your diet. Yes, the array 3 from Cyrex could shed some more light, but so could a genetic test.

Big question: Have you now removed gluten from your diet?

I'm not sure what your symptoms are, and that would help to know also. I'd be happy to help and ensure you're on the right path the regain your health. Consider contacting us for a FREE consultation - call 408-733-0400. We're here to help!

The HealthNOW Doctors said...

@the White family:One option would be to do a genetic test. If your son has one or two of the genes necessary to create celiac disease, then you'd know for sure. There is a relatively inexpensive on-line test: it simply requires swabbing the inside of the mouth.

Beyond that, I'd be happy to talk with you about some other steps you could take beyond just waiting and testing, which could result in damage that could have been avoided. Consider contacting us for a FREE consultation: 408-733-0400. We are here to help!

Anonymous said...

Please help. been suffering since 2000. blood test done in 2008 results:

AGA IGA positive 12.6 reference < 12.0 U/ML
AGA IGG positive 21.6 reference < 12.0 U/ML

TTG (endomysial) negative 1.3 reference < 10.0 U/ML


Unknown said...

Please help. been suffering since 2000. blood test done in 2008 results:

AGA IGA positive 12.6 reference < 12.0 U/ML
AGA IGG positive 21.6 reference < 12.0 U/ML

TTG (endomysial) negative 1.3 reference < 10.0 U/ML


The HealthNOW Doctors said...


I would be delighted to help you. Please give my office a call at 408-733-0400 and we can set up a free phone consultation. You do have a positive test result so we can discuss that too along with getting to know exactly what symptoms you are suffering from.

Dr Vikki Petersen

Unknown said...

My symptoms are gastro (diarhea, bloating like i'm 7 months pregnant) since this past fall it's been joint pain, brain fog, dizzy, forgetfull, irritable, easily annoyed, extreme fatigue even when I have a good night's sleep, constant sinus pain, trouble losing weight despite and balanced whole food diet and exercise itchy blisters filled with clear liquid on my hands (sine 1998) but only appear in August/september.

I also had a biopsy done in 2008. If I read my lab reports correctly, there were two sample taken and there was no damage so I was diagnosed with IBS and told to destress (even though I wasn't stressed) and do yoga.

Please help. I'm tired of suffering.


Rebecca Batdorf said...

My results look different then many examples I see online. Except for the IGA total? I have several health issues and have been working with my doctor and currently have been referred to a gastroenterologist. I have chronic migraines. I have skin hives. I have thyroid disease and had to have a thyroidectomy. So I take levinthroxine and am vitamin D deficient. My big health issue that I'm seeing the specialist for is i get stomach/ abdominal spasms. Fallowed by my quickly having to find a restroom. Sometime the pain from spasms last minutes and sometimes hours. I've recently been expiring a new symptom that I need to call my doctor about because my arms hands and even part of my face have gone numb. Not painful just weird feeling and tingly. My doctor has mentioned auto immune issues as a possible concern since my brother is diagnosed with MS. I did a 3 month diet months back before this testing to see if I was gluten sensitive or dairy sensitive. I still do my best to avoid dairy but I started eating gluten again few months back. I know during my diet change that I didn't 100% not have gluten but for a period of 4 weeks think i didn't have it and I'd swear my symptoms got worse with the diet change.

Component Results
Component Your Value Standard Range
Transglut IgA autab 0.9 u/mL 0.0 - 3.9 u/mL
Negative: 0-3.9 u/mL
Weak Positive: 4.0-10.0 u/mL
Positive: >10.0 u/mL
Transglut IgG autab 2.5 u/mL 0.0 - 5.9 u/mL
Negative: 0-5.9 u/mL
Weak Positive: 6.0-9.0 u/mL
Positive: >9.0 u/mL
Antigliadin Abs, IgA 4.2 units 0.0 - 19.9 units
Negative: 0.0-19.9 units
Weak Positive: 20.0-30.0 units
Moderate to Strong Positive: >30.0 units
Antigliadin IgG 2.7 units 0.0 - 19.9 units
Negative: 0.0-19.9 units
Weak Positive: 20.0-30.0 units
Moderate to Strong Positive: >30.0 units
IgA 192.0 mg/dL 68.0 - 378.0 mg/dL
General Information

Thank you for any help reading this.

Petra K said...

Hi Dr Vikki -

Like many others, I'm hoping you can help me understand my lab results. I read it as negative for Celiac, however, my main complaint is the itchy blistery skin rash that my doc thought might be DH (I have not had a biopsy done). How likely is it to have the results I have (below) and still have DH? What would be your recommended course of action? Thanks!

Immunoglobulin A
Standard Range: 91-414 mg/dL
Your value: 190

Endomysial IGA AB Titer
Standard Range: Negative
Your Value: Negative

Tissue Transglutaminase AB IGA
Standard Range: 0-3 U/mL (Negative 0 – 3; Weak Positive 4 – 10; Positive >10)
Your value: <2

Nana Sun said...

Dear doctor, could you please give a comment on following results:
Gliadin IgG/IgA (DGP) 14 for the normal scale from 0 to 6.90
Immunoglobulin A 17.40 for the normal scale From 21 to 120

That was a result for the blood test for my year and a half daughter. I'm pretty worried for her

Anonymous said...

Looking for some advice. Just a little background, I developed Psoriasis around age 15, diagnosed with psoriatic arthritis at 30, and I'm now 40 with overwhelming fatigue, severe muscle cramps, and GI problems. My blood work is as follows:
IGA. 333 (68-378)
Endomysial ABS IGA. <1:10
tTg IGA <1.2 (<4 neg)
tTg IGG 3.8 (<6 neg)
Gliadin deamd AB IGG. <10 (20 neg)

Vit D 25 HYD TOT 16.7 ( 30-100)
RBC 4.13 (4.20-5.40)
Hg. 12.2 (12.0-16.0)
Hct 35.7 (37.0--47.0)

Total IGG 1374 (700-1600)
Total IGM 224 (40-230)
Total IGE 43.8 (5.8-216)

Any input would help!

Unknown said...

I had the celiac test, don't understand at all. Antigliadin igg 20 the iga is 20, antiendomysial iga negative, tissue transglutaminase iga 4.0, immunoglobulin is383 mg\dl

Anonymous said...


I recently got some lab results back, haven't been able to go to the doctors office yet. I'm not sure if i might have CD or not.

tTg IgA: 72.1
tTg IgG: 11.2

EMA IgA: Negative 1:80
EMA IgG Negative 1:40

The EMA results read negative, but I've been investigating online and it says that values such as 1:80 or 1:40 are indeed positive.

Would appreciate some feedback!


Rebecca Barnett said...

Hi. My son who is almost 4 has had tummy troubles most of his life. He had an endoscopy and colonoscopy last year that showed inflammation in the large colon, small intestine appeared fine after being on a gluten diet for 6 weeks. IBD is suspected. He is very small height/weight.

I'm confused by his blood work in relation to celiac:
- IgG 4.2
- IgA 0.64
- IgM 1.31
- Transglut IGA 0.9

Can you help me understand this blog work?

The HealthNOW Doctors said...

@Rebecca BArnett - Hello. I'm happy to help and need to decide the best approach to assist your son. The test results you sent aren't quite complete. There was likely more data, including reference ranges on the lab test.

When IgG is measured it's typically associated with some other measurement. As you noted on the last value, the IGA was for transglutaminase. It is possible that they only measured total igG, A and M but that's not typical. The tTG value appears negative but I need reference ranges to be sure.

Here's what I suggest:

Consider contacting me at my office (408-733-0400) or via email: so we can speak and best figure out how to help your son.

Dr Petersen

Christine Pett said...

My daughter is now 10. She has a five year history of repeated orthopedic issues - broken foot, broken toe, broken elbow, and chronic Achilles tendonitis in both legs. Recently did a gluten sensitivity test. Results were interpreted as negative:

Total IgA 72 (52-290 mg/dL)
tTG/igA 1.3 (less than 4.0)
DGP 1 (less than 20)
AGA IgA 1 (less than 20)
AGA igG 4 (less than 20)

We went gluten free before getting the test results back and she hadn't complained about Achilles pain one time in three weeks. However, after eating mostly dairy-free also, and suddenly eating a bunch of cheese at dinner the other night, her tendonitis flared up again. Test results also show negative for dairy allergy. Help!

The HealthNOW Doctors said...

@Christine Pett:
Hello. I understand what is occurring and I believe we can help. You sent an email to my office and I've responded offering you a free phone consultation so I can get some more data.

If you see this first please call us at 408-733-0400.

We look forward to assisting!

Anonymous said...

Hi there,
I wanted to check for celiac disease or gluten sensitivity since I have had many symptoms recently and in the past which I've read can be related to having these.
So I consulted my doctor who ordered some tests and got these results:

Gliadin (Deamidated) Ab, IgG 4 (in range) Reference range <20U
Gliadin (Deamidated) Ab, IgA 33H (out of range) Reference range <20U

Reference range for Gliadin (Deamidated) Ab, IgG, IgA:
Antibody Not Detected <20U
Antibody Detected > or = 20 Units

Endomysial Ab IgA Negative

Reticulin IgA Screen Negative

To a non-medical person like me, the only result to be concerned with is the high IgA level of Antibody detected.

My doctor didn't explain too much about the results. Just kept saying the results were "inconclusive" but I should start cutting out gluten from my diet if I haven't already. I think he meant (I know I should have double-checked with him, but other test results took over consultation time) I do not have celiac disease but some kind of high sensitivity to gluten. But what is the difference?

Can someone have high sensitivity to gluten products and experience negative symptoms damaging to mental and physical health?

The HealthNOW Doctors said...

@Anonymous with recent lab test posted 5/10/16
The positive test, Deamidated Gliadin Ab, IgA, with a value of 33, is considered a very sensitive test for celiac disease. As you can see it is out of range, meaning positive.

The fact that other tests are not positive does not negate the presence of a positive value.

The factors required to make a celiac diagnosis are 4 out of 5 of the following factors being present:

1. you have symptoms consistent with celiac disease. This includes a wide range of symptoms and I assume you fall into this category based on your doctor's willingness to perform the tests.

2. you feel better on a gluten-free diet. You may or may not yet know the answer to this question if you haven't begun such a dietary change.

3. You have a positive blood test - this you do have based on what you shared.

4. You have the genes for the disease. This is an easy swab of the inside of the mouth.

5. You have a positive intestinal biopsy. This is an invasive and expensive test and one you don't absolutely need to get if you can get the genetic test described above in #4.

The fact that your doctor was not more clear in laying this out for you concerns me. Clearly there is a health issue here that must be addressed.

The 5 criteria I describe above is accepted world-wide by celiac disease experts - it is not my opinion.

I would be happy to assist you if you need it and always feel free to contact us for a complimentary phone consultation (408-733-0400). We are here to help and as a destination clinic we see patients from across the country and internationally!

Martin Bergmann said...


I got blood work done becaus of unspecific digestion issues .( colonoscopy and stomach check negative )

AT Endomysal IgA,IgG, : 0
( <2.5 Negative , > 40.0 Positive, 2.5-40 Unclear)

AT Anti-gliadin IgG : 3.25 (normal <25)
AT Anti-gliadin IgA : 27.63 (normal <25)

My doctor did say I have celiac disease ... So I did eat 2 years completely gluten free . But I'm not sure anything changed . I'm as well hypochondriac so it's hard for me to determine symptoms .. I can create them :(...

Pease what do u thing ?

Warm regards

sunshynnne said...

My 5 yo had a gi/respiratory bug ( which my daughter also had soon after based on symptoms ) and I'm unsure if this may have affected his following lab values in some way also.. Well he began to complain of stomach pains during this incidence but also few weeks after - after about a month of pain on and off we got regular CMP/CBC and celiac profile labs done via his pedi.. Below are are his results. Please share your thoughts.
Platelets: 492(H) - Normal range 150-450
Neuts: 55.90 (H) - Normal range 27-55
PLT EST: Increased - Normal is normal
Co2: 23 - Normal 24-31
Alk Phos: 178 - Normal 40-150
Values from Celiac Disease Comprehensive by LabCorp are as follows:
Deamidated Gliadin Ab, IgA: 19 - Normal 0 - 19
Deamidated Gliadin Ab, IgG: 31 - Normal 0 - 19
tTG Ab, IgA: 28 - Normal 0 - 3
tTG Ab, IgG: 8 - Normal 0 - 5
Endomysial Ab, IgA: Neg - Normal negative
Serum IgA: 163 - Normal 52 - 221

The HealthNOW Doctors said...

@sunshynne - Thank you for writing. I cannot legally make a diagnosis for a patient I have not examined, but I can speak generally about the test results.

As you've probably surmised, the celiac tests (deamidated gliadin and tTG) are positive. Based on the established criteria for diagnosing celiac disease, if 4 of the following 5 criteria are positive, that is adequate to make a diagnosis.

1. symptoms consistent with the disease - this could be your son's stomach pain but you know his symptoms.
2. positive genetic test - this is easy to get and not invasive. If your doctor won't perform it, consider EnteroLab online - they will send a test kit to you.
3. positive lab test - this is done
4. symptoms improve once gluten has been eliminated
5. positive intestinal biopsy - this is an invasive test that is not mandatory if the other 4 criteria are positive.

It is not unusual for an infection to initiate celiac symptoms.

Please let me know if this is of assistance and what else I can do for you. It's important that everything possible is done to heal you son's intestine and boost his immune system even above eliminating gluten.

If you'd like a free phone consultation consider calling us at 408-733-0400. We are here to help!